Metagenomics Sequencing

microbiome metagenomics sequencing

Metagenomics Sequencing

Microbial communities abound everywhere and exert powerful effects on their surroundings. For example, microbial diversity in the gut microbiome. The trillions of bacteria in the human gut—are associated with disorders ranging from diabetes mellitus and obesity to inflammatory bowel disease to cancer.

Metagenomics can leverage next generation sequencing to rapidly analyze the diversity of microbial communities and elucidate the role of constituent species. We offer a suite of metagenomics sequencing solutions ranging from targeted assays (16S for prokaryotes and ITS for fungi), metabarcoding for higher eukaryotes to whole genome analysis. Learn more below to see which service best fits your research needs.

View our other NGS service here.

16S rRNA Amplicon Sequencing

Microbes Targeted Bacteria and Archaea
Taxon Level Genus/Species
Genomic Loci Sequenced 16S rRNA gene
(V3 and V4 regions)
Application Taxon Identification
Benefits Enhanced sensitivity outperforms
V4-only assays

Fungal Identification

Microbes Targeted Fungi
Taxon Level Genus/Species
Genomic Loci Sequenced Internal Transcribed
Spacer 2 (ITS2)
Application Taxon Identification
Benefits High variation in ITS2
region allows differentiation
between closely related species

Shot-gun Metagenomics

Microbes Targeted All
Taxon Level Sub-species
Genomic Loci Sequenced Whole Genomes
Application Taxon Identification, Variant Discovery
Benefits Phylogenetic analysis; Ideal for organisms with poorly annotated 16S genes

16S/ITS Amplicon Sequencing Bioinformatic Analysis Workflow

mbio 16S metagenomics data analysis

Webinar: Uncovering Hidden Microbial Diversity with NGS Technology

microbiome metagenomics sequencing This webinar outlines the role and importance of microorganisms in our everyday world, how to classify and identify them, and the next generation sequencing techniques that work best for these tasks. We touch on the wide array of areas that microbial genomics can be applied to and the NGS case studies that have helped scientists thrive in various research areas.

Tech Note: Gut Microbiome Research using NGS

Advances in technical capabilities for reading complex human microbiomes are leading to an explosion of microbiome research, leading in turn to intense interest among clinicians in applying these techniques to their patients. Here we would like to share with you a technical notes on Gut Microbiome Research.